Acute Exposure Guidelines Levels for Selected Airborne Chemicals, Volume 6 (2008)Board on Environmental Science and Toxicology
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At the request of the Department of Defense, the National Research Council has reviewed the relevant scientific literature compiled by an expert panel and established Acute Exposure Guideline Levels (AEGLs) for 12 new chemicals. AEGLs represent exposure levels below which adverse health effects are not likely to occur and are useful in responding to emergencies such as accidental or intentional chemical releases in the community, the workplace, transportation, the military, and for the remediation of contaminated sites. Three AEGLs are approved for each chemical, representing exposure levels that result in: 1) notable but reversible discomfort; 2) long-lasting health effects; and 3) life-threatening health impacts. This volume in the series includes AEGLs for chemicals such as ammonia, nickel carbonyl and phosphine, among others.
- AEGL documents for allylamine, ammonia, aniline, arsine, crotonaldehyde, cis/trans-, crotonaldehyde, trans-iso, 1, 1-dimethylhydrazine, iron pentacarbonyl, methyl hydrazine, nickel carbonyl, phosphine, and 8 metal phosphides are each published as an appendix to this report.
- AEGLs represent threshold exposure limits (exposure levels below which adverse health effects are not likely to occur) for the general public and are applicable to emergency exposures ranging from 10 minutes (min) to 8 h. Three levels AEGL-1, AEGL-2, and AEGL-3 are developed for each of five exposure periods (10 min, 30 min, 1 h, 4 h, and 8 h) and are distinguished by varying degrees of severity of toxic effects.
- The committee concludes that the AEGLs developed in these appendixes are scientifically valid conclusions based on the data reviewed by NAC and are consistent with the NRC guideline reports.