Consensus Report

Reproducibility Issues in Research with Animals and Animal Models: Workshop in Brief (2015)

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Scientific progress is achieved by robust experiments that generate reliable and reproducible results to be used with confidence by the research community. Recent publications have drawn attention to an apparent and concerning prevalence in the number of peer-reviewed studies that cannot be reproduced, particularly those containing data from experiments using animals and animal models. At this workshop, organized by the ILAR Roundtable, researchers from around the world explored the many facets of animal-based research that could contribute to irreproducible results, including perspectives on improving experimental planning, design, and execution; the importance of reporting all methodological details; and efforts to establish harmonization principles of reporting on the care and use of animals in research studies.