Study in Progress

Peer Review of the NTP Monograph on Systematic Review of Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects

Statement of Task

An ad hoc committee of the National Academies of Sciences, Engineering, and Medicine will review the National Toxicology Program (NTP) Monograph on Systematic Review of Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects. The committee will provide an overall critique of the draft monograph and address the following questions:

-- Has the systematic review protocol been followed and modifications appropriately documented and justified?
-- Does the monograph accurately reflect the scientific literature?
-- Are the findings documented in a consistent, transparent, and credible way?
-- Are the report's key messages and graphics clear and appropriate? Specifically, do they reflect supporting evidence and communicate effectively?
-- Are the data and analyses handled in a competent manner? Are statistical methods applied appropriately?
-- What other significant improvements, if any, might be made in the document?
-- Does the scientific evidence in the NTP Monograph support NTP's hazard category conclusions for fluoride in children and adults?