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Fourteenth meeting of the Committee on Emerging Issues and Data on Environmental Contaminants
 
Use of Toxicogenomics to Understand Toxic Effects and Improve Risk Assessment: A Workshop

November 13, 2006
Keck Center of the National Academies
Washington, DC
 
8:30 Introduction of the Standing Committee
Kenneth S. Ramos, Health Sciences Center, University of Louisville
 
8:40 Review of Workshop Structure and Organization
Linda E. Greer, Natural Resources Defense Council
 
8:50 Overview of EPA's Risk Assessment on Dibutyl Phthalate
Bob Benson, U.S. Environmental Protection Agency, Region 8
Download Presentation Slides | Audio Clip
 
9:15 Male Reproductive Tract Malformations Induced by Dibutyl Phthalate in the Rat: Developmental Exposure Windows and Implications for Toxicogenomics Analysis
Paul M. Foster, Environmental Toxicology Program, National Institute of Environmental Health Sciences
Download Presentation Slides | Audio Clip
 
9:40 Gene Expression Profiling Reveals New Targets In Phthalate-Induced Testicular Dysgenesis
Kevin W. Gaido, Center for Integrated Genomics, CIIT Centers for Health Research
Download Presentation Slides | Audio Clip
 
10:10 An Approach to Using Toxicogenomics Data in Risk Assessment: Dibutyl Phthalate Case Study
Susan Y. Euling, National Center for Environmental Assessment, U.S. Environmental Protection Agency
Download Presentation Slides | Audio Clip
 
10:30
Break
 
10:45 Overview of US EPA’s Benzene Risk Assessment and Salient Issues
Tracey Woodruff, U.S. Environmental Protection Agency
Download Presentation Slides | Audio Clip
 
11:10 Early Biologic Effect Biomarkers—old and new—in Studies of Workers Exposed to Benzene
Nat Rothman, Qing Lan, National Cancer Institute
Audio Clip
 
11:35 Integration of Toxicogenomics and Mouse Models of Susceptibility to Identify Critical Pathways of Toxicity that Impact Risk
Leslie Recio, Integrated Laboratory Systems Inc.
Download Presentation Slides | Audio Clip
 
12:00 Lunch
 
1:00 Explanation of Breakout Group Objectives and Structure
Linda E. Greer
 
1:10 Discussion of How Current and Future Toxicogenomics Data Might Inform Risk Assessment
 
3:00 Report of Dibutyl Phthalate Breakout Group
Download Presentation Slides for Breakout Group #1
Download Presentation Slides for Breakout Group #2
 
3:55 Report of Benzene Breakout Group
Download Presentation Slides for Breakout Group #1
Download Presentation Slides for Breakout Group #2
 
4:45 Summary
Linda E. Greer
Audio Clip
   .... ....   

The activities of the National Research Council's Committee on Emerging Issues and Data on Environmental Contaminants have now been completed. This website will remain online to serve as a reference to the committee's activities and resource for the accompanying workshop summaries, presentations, and newsletters.

NEW! A new related activity was launched in October, 2008. Please see the National Academies' Standing Committee on Use of Emerging Science for Environmental Health Decisions website for more information.

  
 
 
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