Application of Toxicogenomics to Cross-Species Extrapolation
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| Seventh meeting of the Committee on Emerging Issues and Data on Environmental Contaminants |
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| Applications of Toxicogenomics to Cross Species Extrapolation: A Workshop |
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| August 12, 2004 |
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| 9:00 |
Welcome and Overview of the Workshop, inlucing what is meant by "cross Species Extrapolation" |
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Leigh Anderson and David Eaton |
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Download Presentation Slides | Audio Clip |
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| 9:10 |
Highlights from a recent Pellston Workshop on Emerging Molecular and Computational Approaches for Cross Species Extrapolation |
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Richard Di Giulio, Duke University |
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Download Presentation Slides | Audio Clip |
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| 9:35 |
Potential Implications of genomics for regualtory and Risk Assessment Applications at EPA |
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William Benson, U.S. Environmental Protection Agency |
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Download Presentation Slides | Audio Clip Part I | Audio Clip Part II |
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| 10:00 |
Discussion of Issues |
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Audio Clip Part I | Audio Clip Part II |
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| 10:40 |
Technological challenges of Cross Species Extrapolation Using Poteomics |
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Frank Witzmann, Indiana University |
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Download Presentation Slides | Audio Clip |
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| 11:10 |
Modeling gene Expression Data to Predict Human Hepatotoxicity Following Inconsistent Animal Reponses |
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Donna Mendrick, Gene Logic |
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| 1:00 |
Using Metabolomics/'Omics to Explore Species Differences in Metabolism and Distribution |
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Susan Sumner, Paradigm Genetics |
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| 1:30 |
A Systems Biology Approach to Cross Species Extrapolation |
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Russell Thomas, CIIT Centers for Health Research |
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Download Presentation Slides | Audio Clip Part I | Audio Clip Part II |
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| 2:30 |
Combining transcriptional and Toxicological Approaches to Understanding the Basis of species Differences in Conazole Carcinogenesis |
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Stephen Nesnow, U.S. Environmetal Protection Agency |
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Download Presentation Slides | Audio Clip |
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| 3:00 |
Species Differences in Response to Perfluorooctanoic Acid |
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John Butenhoff, 3M Company |
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Download Presentation Slides | Audio Clip Part I | Audio Clip Part II |
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| 3:30 |
Discussion of Talks |
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Audio Clip |
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| 3:30 |
Roundtable Discussion |
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Audio Clip Part I | Audio Clip Part II |
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| 5:00 |
Adjourn |
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NOTE: These are unedited audio files of the Seventh Meeting of the Committee on Emerging Issues and Data on Environmental Contaminants and is not an official report of National Academy of Sciences, National Academy of Engineering, Institute of Medicine, or National Research Council (collectively “National Academies”). Opinions and statements included in the recorded discussions are solely those of the individual persons or participants at the symposium, and are not necessarily adopted or endorsed or verified as accurate by the National Academies. |
